Sole survivors of a man-made catastrophe that has destroyed earth’s atmosphere, Billy (Mark Duplass) and Ray (Sterling K. Brown) are childhood friends who have managed to embrace the new normal from within their domed biosphere, an artificial ecosystem which Ray - a brilliant scientist - designed to provide them with the necessary life support. When the last female fish in their pond perishes, leaving behind only two male specimens, extinction seems like a given unless life beats the odds and adapts.

Co-written by indie film maverick Mark Duplass and debuting director Mel Eslyn, BIOSPHERE is a two-hander that’s wonderfully carried by Duplass and Brown’s infectious chemistry. As much a buddy comedy as it is a speculative sci-fi chamber piece born from an imaginative ‘what if?’ premise, BIOSPHERE cleverly uses its single location to tackle its ambitious and topical themes in an out-of-the-box manner, transforming itself into one of the most hopeful and encouraging post-apocalyptic survival films ever made.